The people behind the ideas.
The ideas behind the companies.

2nd Watch is a global leader in building, deploying and managing Amazon Web Services based IT operations for enterprise customers.

A-Alpha Bio uses synthetic biology and machine learning to measure and engineer protein-protein interactions and generate high-resolution models of biology for drug discovery. The company has developed a proprietary platform technology, called AlphaSeq, that uses genetically engineered cells to experimentally measure millions of protein-protein interaction affinities simultaneously at a library-on-library scale, generating enormous amounts of data to inform the discovery and development of the next generation of high-impact therapeutics. A-Alpha Bio was founded in 2017 by a team of synthetic biologists from the University of Washington's Institute for Protein Design and Center for Synthetic Biology.

Accolade is an on-demand healthcare concierge for employers, health plans and health systems. Accolade customers experience industry-leading engagement levels, satisfaction scores unseen in healthcare, better health outcomes, and cost savings of 5%-15%.

Algorithmia’s AI Layer managed the machine learning lifecycle and automates the deployment of machine learning models at scale.

Ally was a business and goal management software platform with roots in the OKR (objectives and key results) goal alignment framework that is transforming businesses and employees’ work lives.

Amazon is a Fortune 500 company based in Seattle that seeks to be Earth’s most customer-centric company, where customers can find and discover anything they might want to buy online, and endeavors to offer its customers the lowest possible prices.

Amperity is the leading Customer Data Platform provider that helps companies use data to improve marketing performance, build long-term customer loyalty and drive growth. Amperity's flagship enterprise CDP is used by many of the world's most loved brands, such as Alaska Airlines, Crocs, Endeavour Drinks, Kendra Scott, Kroger, Lucky Brand, Planet Fitness, Seattle Sounders FC, Under Armour and Wyndham Hotels & Resorts.

The founders of Animoto Productions™ share a passion for helping people share their stories and express themselves through online media by innovating technologies in the field of video production.

Anomaly is streamlining healthcare payments—reducing healthcare costs and complexity. Over $300B is lost every year to avoidable denials and payment errors, impacting the affordability of healthcare. Anomaly is working with the country’s largest healthcare companies to enable instant, accurate healthcare payments. Our AI-enabled products integrate in the claims flow, analyzing billions of transactions to predict and prevent payment issues before they occur. Our fast-growing team brings together top engineering and healthcare talent committed to making healthcare more efficient and affordable.

AnsweriQ applied AI to the challenge of customer support ticket routing and helps human customer support agents answer questions faster.

AppFog was the leading polyglot and infrastructure agnostic Platform-as-a-Service provider.

Apptio builds advanced data and analytics applications for Technology Business Management.

Archway is a platform for banks to easily create innovative digital services in weeks, not years. It provides a single access point to seamlessly connect any banking platform to third-party financial software providers — with pre-assembled integrations.

Bizible is a B2B marketing attribution solution that enables hundreds of companies to measure marketing on the basis of revenue.

Bobsled provides a data sharing platform that helps data providers, SaaS companies and other providers of valuable analytics share data products into the platforms where their customers and partners work.

Booster Fuels delivers competitively priced gas to your car while you work.

Buuteeq was an early provider of software for hotels to build and manage websites for marketing and customer reservations.

Cedexis was a real-time, data-driven service for dynamically optimizing the flow of traffic across public clouds, data centers, CDNs, and ISPs.

CommerceIQ is the leading Retail Ecommerce Management Platform, powering profitable market share growth for consumer brands across 450 global online retailers in 41 countries. CommerceIQ’s all-in-one platform applies machine learning across sales, supply chain, and retail media automations, along with digital shelf analytics, to create a single source of truth that empowers brands to boost share-of-voice (SOV), minimize out-of-stock (OOS), optimize assortment and inventory, and prevent revenue leakage. More than 2,200 brands globally, including Nestle, Colgate, and Whirlpool, trust CommerceIQ to manage and grow their retail ecommerce businesses across global retailers including Amazon, Walmart, and Instacart.

Decide was an online shopping research service that predicted whether prices were going up or down on consumer electronics, housewares and other products.

Deepgram is an enterprise automated speech recognition and understanding company that enables companies to build foundational and specialized language models for a range of applications.

DevZero makes developers more productive by providing a platform for cloud-based software development environments that work with all IDEs, existing dev tooling, and enterprise integrations. Their mission is to be the de facto dev platform for modern enterprises.

Envisagenics is an Artificial Intelligence-driven biotechnology company that focuses on the discovery of novel RNA splicing variants that cause cancer and other genetic diseases. Its principal technology is the SpliceCore® discovery platform. The platform re-envisions the human genome with a validated exon-centric approach, combined with machine learning algorithms and high-performance computing. It is up to 250 times more likely to discover novel targets than gene-centric discovery tools. Using innovative technology and RNA analysis expertise, Envisagenics accelerates the development of highly specific therapeutics that modulate RNA splicing events that drive pathogenesis of oncology, neurodegenerative, and metabolic disorders.

Eventbase is the leading mobile app platform for premium events. Trusted by global brands to create event apps for their Tier 1 conferences, Eventbase’s clients include Microsoft, SAP, HP, Cisco, Salesforce, Cannes Lions and South By Southwest (SXSW).

ExtraHop provides cloud-native network detection and response that helps you quickly investigate threats, deliver critical applications, and secure your investment in the cloud.

Go1 delivers an onboarding, compliance and professional development platform for employee education and training.

HelloTech is changing the way consumers purchase and get support for new technology. Utilizing a background- checked, vetted on-demand workforce, HelloTech provides in home support and consultation for consumers looking to manage and upgrade the technology within their home.

Highspot is the sales enablement platform that increases the performance of sales teams. With the content to engage customers, guidance to land strategy, training to improve skills, coaching to elevate performance, and analytics to inform action, Highspot equips every rep to execute with impact — empowering you to drive strategy and revenue with the full force of your sales team. Highspot has more than 1,000 employees, five global offices, and is trusted by companies across industries and geographies, including Aetna, DocuSign, Siemens, Staples, and Yahoo.

Indochino is the world’s premier online custom clothier, specializing in custom suits for men.

iSpot.tv helps advertisers measure the brand and business impact of TV and streaming advertising, from concept to airing to conversion. Fast, accurate and actionable measurement and attribution solutions enable advertisers to assess creative effectiveness, enhance media plans and attribute advertising results for cross-platform campaigns, all while benchmarking against competitors and historical norms. Unlike legacy and ad hoc solutions, iSpot is purpose- built to measure the performance of every ad on television with digital-like precision and granularity in real time. With always-on performance insights unified across linear and streaming TV, advertisers can take quick and confident action to consistently drive business results.

Jama is a cloud-based collaborative solution used by Global 1,000 companies to define, build and test products.

Knock is building a modern marketing cloud for the multifamily property market.

Leaf Logistics was founded in 2017 with the mission to improve transportation planning through strategic use of data analytics and machine learning. The Leaf Grid connects shippers, providers, and partners to gain network efficiencies, reduce their carbon footprint, and unlock a forward view of tomorrow's transportation market. Today, Leaf technologies like the Leaf Adapt continuous optimization solution and Leaf Flex committed contracts allow users to engage in the Grid and build their most resilient transportation plan. Join us at leaflogistics.com.

Lexion is a SaaS application of AI and NLP applied to managing the information buried in corporate contracts.

LumaTax’s mission is to alleviate the burdensome process of state and local tax compliance for the 20 million plus small and medium sized businesses across America.

Magnify is an intelligent application focused on post-sales engagement with customers – providing a platform to consolidate customer interaction data, draw insight, and create cross-functional workflows to improve customer retention, expansion and adoption. Magnify was incubated with Madrona Venture Labs.

Matcherino is an eSports engagement platform. Matcherino gives eSports fans the ability to discover and fund matches they want to see and promotes streamers to new audiences.

Mobilewalla provides innovative AI solutions that give data scientists flexible tools and highly predictive data to improve the feature engineering process, increasing efficiency, and creating high performing machine learning models.

Modulus Therapeutics is a seed-stage cell therapy design studio developing an internal pipeline of NK cell anti-solid tumor programs. Failures in cell therapy efficacy can be traced to poor conceptualization, design and integration of engineered components. Modulus is uniting whole-cell synthetic biology with machine learning into a cell therapy design solution to dramatically reduce pipeline risk and accelerate the path to the clinic. The team is a diverse group of cell therapy veterans along with bioengineering and machine learning experts laser focused on driving therapeutic efficacy by accessing the full cell design space.

MontyCloud is a multi-cloud management and governance company.

Based in Seattle, Washington, Nautilus is a development stage life sciences company creating a platform technology for quantifying and unlocking the complexity of the proteome. Nautilus’ mission is to transform the field of proteomics by democratizing access to the proteome and enabling fundamental advancements across human health and medicine. To learn more about Nautilus, visit www.nautilus.bio

Numbers Station is Automating the Data Stack starting with AI Powered Data Transformation.

Observe is an observability platform that enables finding issues faster, fixing them faster and at a lower cost.

OctoML accelerates AI innovation by making it easy to harness the power of machine learning to build intelligent applications. Using OctoML, customers can deploy ML models to a broad set of devices without specialized ML skills, using established DevOps workflows and tools. OctoML was founded by the creators of Apache TVM, an open source stack for ML portability and performance and a key part of the architecture of popular consumer devices like Amazon Alexa. Founded in 2019, OctoML is based in Seattle, WA, and is backed by Amplify Partners, Madrona Ventures, Addition Capital, and Tiger Global.

Opal is the planning platform that enables brands to show up consistently across all channels. Marketing and communications teams working in Opal collaborate more efficiently, keep everyone in the loop and preview their work through the eyes of their customers. Opal is trusted by renowned companies around the world such as Starbucks, Microsoft and Target.

Otherside AI is building artificial intelligence-powered productivity and communication tools that increase the speed of communication.

Outbound AI is conversation AI built for healthcare. Founded in 2021, the Madrona Venture Labs spinout is breaking new ground with cloud technologies that streamline phone-based administrative work across a wide range of revenue cycle applications. Its AI-first solutions serve as workforce multipliers that drive productivity while improving the daily job experience for human talent. The company’s first SaaS offering, PayerVA™ Console, includes a portfolio of intelligent virtual agents and out-of-the-box automation for claims processing.

Ovation is a next-generation clinical informatics company.

Ozette Technologies, Inc. is engineering a transformative leap in cell discovery and annotation of the human immune system. The Seattle-based (remote-first) life sciences technology startup is building a groundbreaking high-resolution, intelligent, single-cell immune monitoring platform and corpus of high-resolution data leveraging its novel AI technologies. Founded in late 2020, Ozette was spun-out from the Fred Hutchinson Cancer Center and incubated at the Allen Institute for AI. Ozette’s interdisciplinary team is made up of a deep bench of scientists, engineers, and designers with a wide range of experience spanning Genentech, Google, Microsoft, Amazon, Airbnb, and leaders and pioneers in the field of medical research and single cell analysis.

Paro is a curated marketplace connecting freelance finance professionals with mid-market and enterprise companies that are seeking quality subject matter experts for project-based work.

Peach works with local restaurants to deliver lunch to your office via SMS text. Meals are always under $12 with delivery, tax, and tip included.

Pendulum is an AI/ML-powered platform for companies and government organizations to detect and understand harmful narratives on social media platforms and elsewhere.

PlexTrac is a modern collaboration and workflow automation platform for cybersecurity teams.

Plus is a data platform that provides the easiest way to capture, see, and share current data from any source without APIs or complex integrations.

Pluto develops applications for people to communicate within virtual reality. Pluto wants to give people a feeling of connection, no matter where they are.

Polly is a modern workflow measurement solution for collaboration platforms including Slack and Microsoft Teams.

Proof is a startup working to make powerful CRISPR-based molecular testing affordable and accessible to everyone

Pulse Labs is a platform that helps brands design voice apps that real people can understand.

Pulumi is a platform for cloud software development. It is designed for developers and DevOps teams to build and manage cloud native software, from containers, serverless functions, APIs, to infrastructure, using one consistent approach.

Qumulo fundamentally changes how enterprises store and manage enormous numbers of digital assets. By creating the world’s first data-aware scale-out NAS software, Qumulo enables customers to answer critical questions about their data footprint in real-time and at incredible scale.

Read enables better meetings through measurement with a team of products that make up the Chief Meeting Officer Suite. The team of products that make up the Chief Meeting Officer Suite includes Read Meeting Manager, Executive Assistant, and Meeting Navigator, which are designed to deliver insights in and across meetings. Read's mission is to make every human interaction meaningfully better, smarter, and happier starting with the more than 500 million people worldwide using Zoom, Microsoft Teams, Google Meet, and Webex every day.

Rec Room is an online universe where you play and create games with your friends.

RelationalAI is building a groundbreaking relational knowledge graph system for developing intelligent data apps. Knowledge graphs are databases that model business concepts, the relationships between them, and the associated application logic. RelationalAI complements the modern data stack to accelerate the development of intelligent data applications. RelationalAI brings together a team of industry experts and researchers across the globe with an extensive list of innovations and awards. The RelationalAI knowledge graph system is available for early deployments with enterprise customers.

Rigado is a secure edge-as-a-service system for commercial Internet of Things applications, including an edge module, a connectivity gateway and a software platform integrated with leading cloud providers. The company’s products are used for next-generation retail, hospitality services, logistics/supply chain, and building management systems.

Route offers an eCommerce platform enabling consumers to track and protect orders, across merchants, on a post- purchase basis and enables merchants to enrich D2C merchandising capabilities and offload white-glove support.

Rover is an online marketplace that connects pet owners with local pet sitters and real homes in hundreds of cities across the United States.

Runway is building the next generation of creative tools that makes machine learning easy and accessible for all types of creatives. With an active and growing community, Runway is pioneering how content and media are created. With a focus on video automation and synthetic media, Runway reduces the costs of creating visual media across creative industries.

SeekOut is the leading Enterprise Talent Optimization Platform that companies use to quickly hire, grow, and retain great talent while focusing on diversity, technical expertise, and other hard-to-find skillsets. In 2022, SeekOut was named on the Forbes annual list of America’ s Best Startup Employers and CEO Anoop Gupta was crowned GeekWire’s CEO of the Year. Throughout 2021, SeekOut was ranked number two in the B2B category of The Information’s 50 Startups to Watch list, and was included on Madrona’s Intelligent Apps Top 40 list. Founded in 2017, SeekOut has raised $189 million in funding, is backed by Tiger Global Management, Madrona Venture Group, Mayfield, and Founders Circle Capital and is valued at $1.2 billion.

Shippable is a cloud-based continuous integration and delivery platform (CI/CD) that developers use to ship code and deliver app and microservices updates and plans to integrate it into its enterprise+ platform.

Shyft serves the huge market of shift workers worldwide – from retail to food service and beyond. Using their mobile app, workers can easily trade and cover a shift. It is a real time communication system that has been broadly embraced by users.

Sila is a fintech software platform that provides payment infrastructure as a service, a business-critical element for all companies that need to integrate with the US banking system and blockchain quickly, securely, and in compliance with applicable US regulation. Sila offers Banking, Digital Wallet & ACH Payments APIs for Software Teams. The firm was recognized as a ‘2021 best place to work in financial technology’. Sila is headquartered in Portland, Oregon.

Skytap is a global cloud provider that accelerates enterprise innovation by modernizing traditional applications with cloud-native development and services.

Spice AI is the fastest, smartest, and easiest way to access web3 data and to build data and AI-driven apps. Spice AI removes the complexity of managing AI infrastructure, providing developers and engineers with the technology and tools to deliver the next generation of apps.

Spotnana powers unparalleled global travel experiences. We are rebuilding the infrastructure of the travel industry in order to bring freedom, simplicity, and trust to travelers everywhere. Our Travel-as-a-Service platform enables corporations, agencies, suppliers, and technology providers to personalize travel booking, lower operating costs, and build deeper customer relationships.

Stack is the first crypto education and trading app for teens and their parents.

Statsig is a Modern Product Experimentation platform that, unlike other A/B testing tools, tracks the impact of every single feature release thereby quantifying impact of all efforts. The “observability” nature of Statsig lets teams catch metric drops within hours of launching features, divest quickly on features that aren’t working, and invest more on the ones that do. The team behind Statsig comes from Facebook and is rebuilding the entire set of data tools infrastructure that powered all of Facebook’s growth in the last decade.Companies like Notion, Flipkart, Ancestry, Whatnot and OpenSea use Statsig to power their modern stack and have shown marked increase in product velocity since adoption.

Stratify enables organizations to collaboratively create operating budgets, monitor performance, and analyze their business in real time. Designed by finance professionals, Stratify connects to every system that runs your business. We provide guided workflows for coordinated, data-informed planning, and automatically generate analytics that have historically burdened finance teams and are stale upon delivery. Stratify is a machine learning-based, intelligent application. We proactively identify business insights and empower finance teams and budget owners to evolve their business in changing market environments.

Strike Graph simplifies security certifications, such as SOC 2, ISO 27001, HIPAA, PCI DSS, GDPR, and more, so companies can focus on driving their business forward. Our innovative, easy-to-use platform adapts to your company’s specific needs and then integrates with common business systems and infrastructure to automatically collect evidence for auditor review. Strike Graph empowers companies to create trust, pass audits, and close enterprise deals at a fraction of the time and cost of traditional methods. Helps companies prepare for, complete and maintain their security certifications such as SOC 2, FedRAMP and ISO, via an intelligent application.

Tangibly's platform enables companies to implement best-in-class management of their trade secrets. Trade secrets can be almost anything, from algorithms to chemical processes to client lists and are among the most valuable assets for many companies. Tangibly helps streamline and simplify legal requirements and implement best practices to establish company assets as legally protectable trade secrets. These best practices include cataloging assets, acknowledgment workflow, access management, tracking required legal agreements (NDAs, employment agreements, partnership agreements, etc.), as well as employee/partner education and training

Founded in 2017, TaskHuman is the world’s first real-time digital coaching platform, allowing users to amplify their daily work and personal life with 1:1 personalized guidance from LIVE specialists over video calls. With TaskHuman, instantly discover and connect with the world’s most comprehensive global network of coaches, instructors, and specialists covering over 1,000 aspects of your well-being, such as physical fitness, mental well-being, spiritual, emotional, financial, career & leadership coaching, and more. With this platform, users can focus on self care anytime — privately and cost effectively. The company has over 100 full-time team members and more than 1,000 coaches around the world across nearly 50 different countries. TaskHuman is backed by USVP, Impact Ventures, Madrona, RingCentral Ventures, and several notable individual investors.

TaxBit is a cryptocurrency tax software for consumers, enterprises, and governments.

Temporal is an open-source microservices orchestration engine for running mission-critical code at any scale.

TerraClear frees farmers from the worst jobs on the farm. Founded in 2017, TerraClear integrates computer vision, artificial intelligence, and robotics to automate what many consider the most frustrating problem in agriculture—rock removal. Impacting hundreds of millions of acres around the world, TerraClear is transforming this manual and slow task into state of the art solutions that work for every farmer. TerraClear’s diverse team of farmers, engineers, and business leaders is passionate about solving the labor crisis in agriculture one painful job at atime.

Terray Therapeutics is an emerging biotechnology company led by pioneers and long-time leaders in AI, medicinal chemistry, biology and preclinical development, automation, and nanotechnology to propel drug discovery into the information age. Terray’s proprietary integrated computational and experimental platforms generate massively scaled, powerfully agnostic chemical data that are purpose-built to power computational learning and reveal new interactions. This foundation is building an iterative, flexible chemistry engine that aims to deliver more precise therapies to patients faster than ever before.

Tesorio is revolutionizing the way B2B businesses manage their Accounts Receivables. Tesorio’s Accounts Receivable platform replaces tedious and manual collections processes with accurate, real-time predictions, optimized workflows, and actionable insights based on behavioral trends. Accounting teams are empowered to achieve breakthrough cash flow performance and predictability while improving customer experience and relationships. Tesorio is trusted by the world's best finance teams at companies like Slack, Box, Veeva Systems, Twilio, Domo, and others. The company has raised a total of $37.6 million in funding to date from investors such as Madrona Venture Group, BAMCAP, First Round Capital, Floodgate, and Y Combinator.

The Riveter is a female-forward workspace and community designed for business and impact.

Tier 3 was a Seattle-based infrastructure as a service (IaaS) platform and advanced cloud management company

Tigera provides the industry’s only active Cloud- Native Application Protection Platform (CNAPP) with full-stack observability for containers, Kubernetes, and cloud. The company’s platform prevents, detects, troubleshoots, and automatically mitigates exposure risks of security issues in build, deploy, and runtime stages. Tigera delivers its platform as a fully managed SaaS (Calico Cloud) or a self-managed service (Calico Enterprise). Its open-source offering, Calico Open Source, is the most widely adopted container networking and security solution. Tigera’s platform specifies security and observability as code to ensure consistent enforcement of security policies, which enables DevOps, platform, and security teams to protect workloads, detect threats, achieve continuous compliance, and troubleshoot service issues in real time. Powering more than 100M containers across 2M+ nodes in 166 countries, Calico software is supported across all major cloud providers and Kubernetes distributions, and is used by leading companies including AT&T, Discover, Merck, ServiceNow, HanseMerkur, RealPage, L3Harris, and Mindbody.

Trade is the leading coffee marketplace connecting the best independent roasters to customers across the country.

Troop is a next-generation corporate travel meeting management platform.

Headquartered in Portland, Oregon, TrovaTrip is the first travel planning and booking platform that connects creators and communities directly with tour operators to offer unforgettable group travel experiences around the globe. TrovaTrip makes it possible for topic experts, creatives, and entrepreneurs to host trips around the globe with their communities. With itineraries in 49 different countries and over 15,000 Travelers booked, TrovaTrip is changing the way people see and connect with the world by enabling them to follow their passion while traveling. Enhancing lives through meaningful connections, learning and exploration, TrovaTrip’s mission is to make travel safer and more accessible to all.

TwinStrand Biosciences is a Seattle genomics company building a platform around Duplex Sequencing, a proprietary process that helps physicians, patients and drug researchers make life saving decisions faster based on DNA data.

Unearth delivers a cloud-native collaboration and communication platform for building physical infrastructure from scratch or maintaining existing assets.

Uplevel gives you a data-driven look into your engineering efforts, providing the business intelligence you need to report on team impact — without micromanaging your people. We measure a multitude of data points that reveal indicators of work, focus, collaboration, and process. To do this, we look to the everyday engineering tools that software developers use to get work done, such as code repositories, messaging apps, and calendars (e.g., Github, Jira, Slack/Teams, Gerritt, and more). You get a powerful data platform plus a team of consultants to analyze your data, helping identify blockers to success across your people and operational health.

Visual Layer is a visual asset management platform for the era of generative AI. With Visual Layer you can simplify visual data ops, ingest data from any source, gain insights, and automatically find and fix data quality issues.

As teams across industries adopt AI, WhyLabs enables them to operate with certainty by providing model monitoring, preventing costly model failures, and facilitating cross-functional collaboration. Incubated at the Allen Institute for AI, WhyLabs is a privately-held, venture-funded company based in Seattle.

Wonder Workshop is a platform that makes programming fun and accessible for children while they play.

Wrench brings the mechanic to your car, making maintenance and repair easy and convenient.

Yieldex was a market leader in publisher forecasting, pricing, and direct-sales analytics tools.

Yoodli is developing an AI-powered technology that provides feedback on your communication skills.

Zeitworks is building a process mining SaaS product to automatically map, measure, and improve business processes across applications, without IT integrations, consultants, interviews, or workshops.