The people behind the ideas.
The ideas behind the companies.

SeekOut
SeekOut’s
Anoop Gupta
on hiring and untapped talent pools
Common Room
Common Room’s
Linda Lian
on integrating community into your company
Pendulum
Pendulum’s
Mark Listes
on finding hidden narratives in social media
OctoML
OctoML’s
Luis Ceze
on bringing ML to all platforms
Flexe
Flexe’s
Karl Siebrecht
on transforming the logistics industry
Spotnana
Spotnana’s
Sarosh Waghmar
on challenging a decades-old industry
Highspot
Highspot’s
Robert Wahbe
on customers, AI, and building relationships that last
Nautilus Bio
Nautilus Bio’s
Sujal Patel and Parag Mallick
on the proteome
Sila
Sila’s
Shamir Karkal
on the digital payments revolution

Company List

  • A-Alpha Bio
    A-Alpha Bio uses synthetic biology and machine learning to measure and engineer protein-protein interactions and generate high-resolution models of biology for drug discovery. The company has developed a proprietary platform technology, called AlphaSeq, that uses genetically engineered cells to experimentally measure millions of protein-protein interaction affinities simultaneously at a library-on-library scale, generating enormous amounts of data to inform the discovery and development of the next generation of high-impact therapeutics. A-Alpha Bio was founded in 2017 by a team of synthetic biologists from the University of Washington's Institute for Protein Design and Center for Synthetic Biology.
    Initial Investment
    2019
    A-Alpha Bio uses synthetic biology and machine learning to measure and engineer protein-protein interactions and generate high-resolution models of biology for drug discovery. The company has developed a proprietary platform technology, called AlphaSeq, that uses genetically engineered cells to experimentally measure millions of protein-protein interaction affinities simultaneously at a library-on-library scale, generating enormous amounts of data to inform the discovery and development of the next generation of high-impact therapeutics. A-Alpha Bio was founded in 2017 by a team of synthetic biologists from the University of Washington's Institute for Protein Design and Center for Synthetic Biology.
    Founders
    David Younger
    Randolph Lopez
    Initial Investment
    2019
  • Accolade
    Accolade is an on-demand healthcare concierge for employers, health plans and health systems. Accolade customers experience industry-leading engagement levels, satisfaction scores unseen in healthcare, better health outcomes, and cost savings of 5%-15%.
    Initial Investment
    2016
    Accolade is an on-demand healthcare concierge for employers, health plans and health systems. Accolade customers experience industry-leading engagement levels, satisfaction scores unseen in healthcare, better health outcomes, and cost savings of 5%-15%.
    CEO
    Rajeev Singh
    Investment Journey
    Public July 2020
    NASDAQ: ACCD
    Initial Investment
    2016
  • Envisagenics
    Envisagenics is an Artificial Intelligence-driven biotechnology company that focuses on the discovery of novel RNA splicing variants that cause cancer and other genetic diseases. Its principal technology is the SpliceCore® discovery platform. The platform re-envisions the human genome with a validated exon-centric approach, combined with machine learning algorithms and high-performance computing. It is up to 250 times more likely to discover novel targets than gene-centric discovery tools. Using innovative technology and RNA analysis expertise, Envisagenics accelerates the development of highly specific therapeutics that modulate RNA splicing events that drive pathogenesis of oncology, neurodegenerative, and metabolic disorders.
    Initial Investment
    2018
    Envisagenics is an Artificial Intelligence-driven biotechnology company that focuses on the discovery of novel RNA splicing variants that cause cancer and other genetic diseases. Its principal technology is the SpliceCore® discovery platform. The platform re-envisions the human genome with a validated exon-centric approach, combined with machine learning algorithms and high-performance computing. It is up to 250 times more likely to discover novel targets than gene-centric discovery tools. Using innovative technology and RNA analysis expertise, Envisagenics accelerates the development of highly specific therapeutics that modulate RNA splicing events that drive pathogenesis of oncology, neurodegenerative, and metabolic disorders.
    Founders
    Maria Luisa Pineda
    Martin Akerman
    Initial Investment
    2018
  • Modulus Therapeutics
    Modulus Therapeutics is a seed-stage cell therapy design studio developing an internal pipeline of NK cell anti-solid tumor programs. Failures in cell therapy efficacy can be traced to poor conceptualization, design and integration of engineered components. Modulus is uniting whole-cell synthetic biology with machine learning into a cell therapy design solution to dramatically reduce pipeline risk and accelerate the path to the clinic. The team is a diverse group of cell therapy veterans along with bioengineering and machine learning experts laser focused on driving therapeutic efficacy by accessing the full cell design space.
    Initial Investment
    2021
    Modulus Therapeutics is a seed-stage cell therapy design studio developing an internal pipeline of NK cell anti-solid tumor programs. Failures in cell therapy efficacy can be traced to poor conceptualization, design and integration of engineered components. Modulus is uniting whole-cell synthetic biology with machine learning into a cell therapy design solution to dramatically reduce pipeline risk and accelerate the path to the clinic. The team is a diverse group of cell therapy veterans along with bioengineering and machine learning experts laser focused on driving therapeutic efficacy by accessing the full cell design space.
    Founders
    Bryce Daines
    Max Darnell
    Initial Investment
    2021
  • Nautilus Bio
    Based in Seattle, Washington, Nautilus is a development stage life sciences company creating a platform technology for quantifying and unlocking the complexity of the proteome. Nautilus’ mission is to transform the field of proteomics by democratizing access to the proteome and enabling fundamental advancements across human health and medicine. To learn more about Nautilus, visit www.nautilus.bio
    Initial Investment
    2018
    Based in Seattle, Washington, Nautilus is a development stage life sciences company creating a platform technology for quantifying and unlocking the complexity of the proteome. Nautilus’ mission is to transform the field of proteomics by democratizing access to the proteome and enabling fundamental advancements across human health and medicine. To learn more about Nautilus, visit www.nautilus.bio
    Founders
    Sujal Petal
    Parag Mallick
    Investment Journey
    Public June 2021
    NASDAQ: NAUT
    Initial Investment
    2018
  • Outbound AI
    Outbound AI is applying conversational AI to healthcare operations.
    Initial Investment
    2021
    Outbound AI is applying conversational AI to healthcare operations.
    Founders
    Stead Burwell
    Jonathan Wiggs
    Kshitij Moghe
    Justin Ith
    Initial Investment
    2021
  • Ovation
    Ovation is a next-generation clinical informatics company.
    Initial Investment
    2019
    Ovation is a next-generation clinical informatics company.
    CEO
    Curt Medeiros
    Initial Investment
    2019
  • Ozette
    Ozette Technologies, Inc. is engineering a transformative leap in cell discovery and annotation of the human immune system. The Seattle-based (remote-first) life sciences technology startup is building a groundbreaking high-resolution, intelligent, single-cell immune monitoring platform and corpus of high-resolution data leveraging its novel AI technologies. Founded in late 2020, Ozette was spun-out from the Fred Hutchinson Cancer Center and incubated at the Allen Institute for AI. Ozette’s interdisciplinary team is made up of a deep bench of scientists, engineers, and designers with a wide range of experience spanning Genentech, Google, Microsoft, Amazon, Airbnb, and leaders and pioneers in the field of medical research and single cell analysis.
    Initial Investment
    2021
    Ozette Technologies, Inc. is engineering a transformative leap in cell discovery and annotation of the human immune system. The Seattle-based (remote-first) life sciences technology startup is building a groundbreaking high-resolution, intelligent, single-cell immune monitoring platform and corpus of high-resolution data leveraging its novel AI technologies. Founded in late 2020, Ozette was spun-out from the Fred Hutchinson Cancer Center and incubated at the Allen Institute for AI. Ozette’s interdisciplinary team is made up of a deep bench of scientists, engineers, and designers with a wide range of experience spanning Genentech, Google, Microsoft, Amazon, Airbnb, and leaders and pioneers in the field of medical research and single cell analysis.
    Founders
    Ali Ansary
    Greg Finak
    Evan Greene
    Raphael Gottardo
    Initial Investment
    2021
  • Proof Diagnostics
    Proof is a startup working to make powerful CRISPR-based molecular testing affordable and accessible to everyone
    Initial Investment
    2020
    Proof is a startup working to make powerful CRISPR-based molecular testing affordable and accessible to everyone
    Founders
    Feng Zhang
    Jonathan Gootenberg
    Omar Abudayyeh
    Siddharth Shenai
    Initial Investment
    2020
  • Saykara
    Saykara provides an AI-powered, voice activated virtual scribe for physicians.
    Initial Investment
    2017
    Saykara provides an AI-powered, voice activated virtual scribe for physicians.
    Founder
    Harjinder Sandu
    Investment Journey
    Acquired by Nuance 2021
    Initial Investment
    2017
  • Terray
    Terray Therapeutics is an emerging biotechnology company led by pioneers and long-time leaders in AI, medicinal chemistry, biology and preclinical development, automation, and nanotechnology to propel drug discovery into the information age. Terray’s proprietary integrated computational and experimental platforms generate massively scaled, powerfully agnostic chemical data that are purpose-built to power computational learning and reveal new interactions. This foundation is building an iterative, flexible chemistry engine that aims to deliver more precise therapies to patients faster than ever before.
    Initial Investment
    2020
    Terray Therapeutics is an emerging biotechnology company led by pioneers and long-time leaders in AI, medicinal chemistry, biology and preclinical development, automation, and nanotechnology to propel drug discovery into the information age. Terray’s proprietary integrated computational and experimental platforms generate massively scaled, powerfully agnostic chemical data that are purpose-built to power computational learning and reveal new interactions. This foundation is building an iterative, flexible chemistry engine that aims to deliver more precise therapies to patients faster than ever before.
    Founders
    Jacob Berlin
    Eli Berlin
    Initial Investment
    2020
  • TwinStrand
    TwinStrand Biosciences is a Seattle genomics company building a platform around Duplex Sequencing, a proprietary process that helps physicians, patients and drug researchers make life saving decisions faster based on DNA data.
    Initial Investment
    2019
    TwinStrand Biosciences is a Seattle genomics company building a platform around Duplex Sequencing, a proprietary process that helps physicians, patients and drug researchers make life saving decisions faster based on DNA data.
    Founder
    Jesse Salk
    Initial Investment
    2019